Recombinant CD147 anticorps

N° du produit ABIN7543034

Cet anticorps Lapin Chimeric détecte spécifiquement CD147 dans WB, FACS, IHC et IP. Il présente une réactivité envers Souris.

Aperçu rapide pour Recombinant CD147 anticorps (ABIN7543034)

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD147 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: OX-114

Détail du produit anti-CD147 anticorps

Fonction: Anti-CD147 [OX-114], Rabbit IgG, kappa

Specificité: OX-114 binds to both the 2- and 3-domain isoforms of CD147. CD147 targets monocarboxylate transporters to the plasma membrane, and is involved in spermatogenesis, embryo implantation, neural network fomration and tumor progression. Stimulates production of matrix metalloproteases. Possibly a receptor for oligomannosidic glycans. CD147 found only in vascular endothelium in non-neoplastic regions of the brain whereas it is present in tmour cells but not in proliferating blood vessels in malignant gliomas.

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: OX-114 was generated by immunizing rats with recombinant mCD147d0-2rCD4d3+4.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody binds mouse CD147, and has been used in FC and IHC-fr analysis to characterise CD147 and detect the cell types on which it is expressed, indicating that CD147 is a lymphocyte activation marker (Paterson, 1987). This antibody failed to give immunoprecipitates from radiolabelled activated T cells.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD147

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Autre désignation: CD147

Sujet: Basigin, basic immunoglobulin superfamily, HT7 antigen, membrane glycoprotein gp42, gp42, gp-42, OX114, MRC OX-114, MRC OX114

UniProt: P18572

Pathways: S100 Proteins